v4.0 · Active developmentContacto: Neumología · CHUAC
Which institution are you searching from?
This helps us track which variants are most searched at each clinical centre — enabling regional prevalence insights and prioritising research gaps by institution.
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—Variants
—ETI Responsive
—Missing Data
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Export options
v3.0-β · En desarrolloContacto: Neumología · CHUAC
Select a variant
Choose a CFTR variant from the explorer to view comprehensive clinical data,
therapeutic predictions, and evidence chain.
${k === 'HitRate' ? 'Search hit rate' : k === 'Responsive' ? 'ETI responsive' : k}
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Research priority queue — variants needing attention
Sorted by gap score
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High priority variantssearched · unvalidated
Miss queue — top gapsby unique users
Platform health snapshot
Total searches
0
this session
Hit rate
—
exact match
Unique queries
0
distinct terms
Miss queue
0
no result found
Search activity — hits vs misses over session
Bars = volume · Line = hit rate %
Top hit variants
by frequency
No searches yet
Top misses research gap
by unique users
No misses yet
DB coverage
—clinical coverage
0%50%100%
Search more variants to build coverage data.
Nomenclature used by clinicians
No data
Breakdown appears after searches.
Miss queue — research gap work items
Sorted by unique users · not raw count
Query not foundUsersCount
No misses recorded yet.
Geographic intelligence
TimelineLive
—searches
—locations
—hit rate
—institution
CFTR class
I
II
III
IV
V
—
High hit rate
Mixed
High miss rate
Top variant by region—
Select a location
Click any marker on the map to explore its search activity
Unresolved queries — ranked by institutional reach—
Select a miss query to see its geographic spread
Compare two locations:vs
Select location A
Select location B
Research gap queue
scored client-side
Variants are scored when selected
LevelVariantScoreSearched
Select variants to populate gap analysis.
Critical gaps
0
variants scoring 80+
Avg gap score
—
across scored variants
Search velocity heatmap
Hour of day × day of week — intensity = search volume from DB logs
Co-search clusters
Variants searched together in the same session — potential compound het pairs
Recent searches — this session
Last 20 · not persisted
No searches this session yet.
All Evidence Sources
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Add Evidence Link
Adding to
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Write mode lasts 30 minutes · Read-only access is always available without a PIN
Helios
AI Evidence Bot · NeumuacFQ
Idle
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Good morning
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est. minutes
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Variants in DB
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Pending Review
External Sources
PubMed / NCBI
pubmed
CFTR2 Database
cftr2
ClinVar
clinvar
Internal DB Consistency
internal
Scan Controls
Scanning…0%
Console
Live
--:--:--☀ Helios initialized. Ready.
Scan Run History
Run a scan to see history
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Issues Found
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Complete Records
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Orphan Variants
Internal Consistency Checks
Click "Run Check" to analyse DB consistency
Monitor Targets
Variants under continuous watch
No variants monitored yet. Select a variant and click Monitor.
Decision Audit Trail
Immutable — all decisions signed
No decisions recorded yet
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Total Variants
—
Validated
—
Unvalidated
—%
Validation Rate
Validation Priority Queue
Ordered by clinical urgency
Click Refresh to load the validation queue
Geographic Demand Signal
Cross-institutional variant demand
Click Analyse to detect cross-institutional demand patterns
AI Feedback Calibration
Approval rates by scan source · updates in real time
Every approve/reject decision trains the AI. Sources with <15% approval (after 5+ decisions) are automatically suppressed. Sources with >70% approval get boosted confidence scores.
No feedback data yet — approve or reject items to calibrate the AI
Suppressed Sources
Sources the AI has learned to ignore
Suppressed scan sources are silenced — Helios will not queue new items from them until the suppression is lifted. Reset calibration to re-enable all sources.
